Parkinson disease - physiology, pathology, clinical manifestations, diagnosis, treatment

What is Parkinson disease? Parkinson disease is a neurodegenerative condition caused by the progressive loss of dopaminergic neurons in the substantia nigra. It is characterized by a classic triad of motor symptoms, which include bradykinesia, rigidity, and resting tremor. Find our full video library only on Osmosis: http://osms.it/find-more. We are re-posting this video to fix the sound issue from the version posted last weekend. Thank you for bringing that to our attention! Join millions of current and future clinicians who learn by Osmosis, along with hundreds of universities around the world who partner with Osmosis from Elsevier to make medical and health education more engaging and efficient. We have unparalleled tools and materials to prepare you for success in school, on your board exams, and as a future clinician. Sign up for a free trial at http://osms.it/free-trial. If you're interested in exploring an institutional partnership, visit osmosis.org/educators to request a personalized demo. Follow us on social: Facebook: http://osms.it/facebook Twitter: http://osms.it/twitter Instagram for med: http://osms.it/instagram Instagram for nursing: https://osms.it/ignursing TikTok: https://osms.it/tiktok LinkedIn: https://osms.it/linkedin Our Vision: Everyone who cares for someone will learn by Osmosis. Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here: http://osms.it/mission Medical disclaimer: Osmosis from Elsevier does not provide medical advice. Osmosis from Elsevier and the content available on the Osmosis from Elsevier properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed healthcare provider. Always seek the advice of a physician or other qualified healthcare professional with any questions you have regarding a medical condition. © 2026 Elsevier. All rights reserved.