How Stress & Diet May Disrupt Brain Energy (Creatine Link)

Deep dive here: https://staycuriousmetabolism.substack.com/p/if-you-have-depression-you-need-to?r=40ekz2 New research suggests that stressors can alter the gut microbiome in ways that reduce creatine absorption, potentially impacting brain energy metabolism and contributing to depression. A randomized controlled trial also found that combining a specific probiotic with creatine may improve depressive symptoms in humans. While links to ultra-processed foods remain speculative, early insights highlight how diet and environment may influence mental health at a metabolic level. For the full mechanisms, limitations, and nuance, watch the long-form breakdown linked above. ⸻ #MentalHealth #GutBrainAxis #Microbiome #Creatine #DepressionResearch #NutritionScience #StayCurious