Sleep in Alzheimer Disease: S8-Ep2

Alzheimer's disease is the most common form of dementia. In this podcast, we discuss the intimate relationship between sleep, sleep disorders and Alzheimer's disease. 0:00  Introduction: Sleep and Alzheimer’s Disease 0:39  Why Sleep Matters for Dementia Risk 0:57  Short Sleep and Dementia Risk 2:26  Glymphatic System and Brain Clearance 3:22  Multifactorial Causes of Dementia 4:11  Sleep Apnea, Amyloid, and Mechanisms 6:26  Does Treating Sleep Apnea Help? 7:10  Interpreting Large Database Studies 8:43  How Alzheimer’s Disease Changes Sleep 9:27  REM Sleep, Lewy Body Disease, and Atonia 11:07  Nocturnal Confusion and Wandering 14:00  Managing Nocturnal Confusion 14:54  Medications and Environmental Strategies 16:21  Sleep Medications: Melatonin to Suvorexant 18:10  Antipsychotics and Safety Considerations 19:12  Key Takeaways on Sleep and Dementia 20:20  Closing